Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083549 | 0.85 | ALDH1A1 (0.32) | ADORA3ADORA1ALDH1A1 | |
| SCHEMBL9082975 | 0.83 | ALOX5 (0.44) | ALOX5PPARGKDM4ELMNAALDH1A1 | |
| SCHEMBL13851483 | 0.83 | ALOX5 (0.44) | ALOX5PPARGKDM4ELMNAALDH1A1 | |
| SCHEMBL13851482 | 0.83 | ALOX5 (0.44) | ALOX5PPARGKDM4ELMNAALDH1A1 | |
| SCHEMBL16160330 | 0.78 | CYP1A2 (0.44) | KDM4ELMNAADORA3ADORA1ALDH1A1 | |
| SCHEMBL9388237 | 0.78 | ADORA3 (0.41) | ALOX5PPARGADORA3ADORA1ALDH1A1 | |
| SCHEMBL9401416 | 0.76 | CYP1A2 (0.42) | KDM4EADORA3ADORA1ALDH1A1 | |
| SCHEMBL9388253 | 0.76 | LMNA (0.38) | KDM4ELMNAADORA3ADORA1ALDH1A1 | |
| SCHEMBL9082706 | 0.75 | KDM4E (0.39) | ALOX5PPARGKDM4ELMNAADORA3 | |
| SCHEMBL9084366 | 0.75 | EDNRB (0.44) | LMNAEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601155-A1 | PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY | Novartis AG (CH) | 1994-06-15 | — | — | EP | claimed |
| WO-1993025540-A1 | PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY | CIBA-GEIGY AG (CH) | 1993-12-23 | — | — | WO | claimed |
| US-5482920-A | Triazinyl compounds with herbicidal activity | CIBA-GEIGY CORPORATION (US) | 1996-01-09 | — | — | US | disclosed |
| EP-0601155-A1 | PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY | Novartis AG (CH) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993025540-A1 | PYRIMIDINYL-AND TRIAZINYL COMPOUNDS WITH HERBICIDAL ACTIVITY | CIBA-GEIGY AG (CH) | 1993-12-23 | — | — | WO | disclosed |