Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099082 | 0.79 | CTSK (0.51) | CTSBCTSKLNPEPERAP2ERAP1 | |
| SCHEMBL9099075 | 0.79 | CTSB (0.51) | CTSBCTSKLNPEPERAP2ERAP1 | |
| SCHEMBL19280973 | 0.73 | KMT2A (0.45) | CASP3KMT2A | |
| SCHEMBL29536591 | 0.73 | CTSK (0.61) | CTSBCTSKLNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7377191 | 0.72 | CTSK (0.58) | CTSBCTSKLNPEPERAP2ERAP1 | |
| SCHEMBL7707279 | 0.71 | KMT2A (0.44) | CASP3KMT2A | |
| SCHEMBL19820407 | 0.71 | CTSB (0.50) | CTSBCTSKCASP3PTPN1 | |
| SCHEMBL20184843 | 0.71 | KMT2A (0.47) | CASP3KMT2A | |
| SCHEMBL27960451 | 0.71 | KMT2A (0.47) | CASP3KMT2A | |
| SCHEMBL30341743 | 0.70 | KMT2A (0.49) | CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732399-A2 | Chymotrypsin-like proteases and their inhibitors | CEPHALON, INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0518955-A4 | CHYMOTRYPSIN-LIKE PROTEASES AND THEIR INHIBITORS | — | 1993-09-22 | — | — | EP | disclosed |
| EP-0518955-A1 | CHYMOTRYPSIN-LIKE PROTEASES AND THEIR INHIBITORS | CEPHALON, INC. (US) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013904-A1 | CHYMOTRYPSIN-LIKE PROTEASES AND THEIR INHIBITORS | CEPHALON, INC. (US) | 1991-09-19 | — | — | WO | disclosed |