SCHEMBL9106447

SCHEMBL9106447

O=S(=O)(O[I+](c1ccc(Oc2ccccc2)cc1)c1ccc(-c2ccccc2)cc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 4/20 0.36
BCL2L1 Q07817 3/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
SDHB P21912 1/20 0.34
CA1 P00915 6/20 0.34
CA2 P00918 6/20 0.34
CA9 Q16790 2/20 0.34
GSTP1 P09211 1/20 0.34
SOS1 Q07889 1/20 0.34
PTPN1 P18031 1/20 0.33
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
AR P10275 1/20 0.32
ESR2 Q92731 1/20 0.32
ADAMTS4 O75173 1/20 0.32
XDH P47989 1/20 0.32
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51423 0.84 CA2 (0.39) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL59304 0.82 CA2 (0.40) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL444424 0.82 CA2 (0.40) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL1804139 0.82 GAA (0.35) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL1800748 0.81 CA1 (0.34) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL1805423 0.80 CA1 (0.35) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL3284035 0.79 CA2 (0.36) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL7045992 0.78 CA2 (0.51) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL2922354 0.78 CA2 (0.37) CA1CA2CA9PDK1PDK2
SCHEMBL6474468 0.77 CA2 (0.50) PIK3CDPIK3CAPIK3CBCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932797-B2 Photoacid generators DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-20120141939-A1 PHOTOACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120141939-A1 PHOTOACID GENERATORS F10, GNG2, H1-0 MCL1 4269/4885BCL2L1 3416/4885PIK3CD 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.