Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25329704 | 0.91 | NFE2L2 (0.50) | NFE2L2TTRFDPSKDM4EALDH1A1 | |
| SCHEMBL29579523 | 0.91 | NFE2L2 (0.50) | NFE2L2TTRFDPSKDM4EALDH1A1 | |
| SCHEMBL646207 | 0.91 | NFE2L2 (0.50) | NFE2L2TTRFDPSKDM4EALDH1A1 | |
| SCHEMBL647362 | 0.88 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| 2,4-Dihydroxybenzophenone SCHEMBL23174978 | 0.77 | ALDH1A1 (0.48) | TTRKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL730348 | 0.75 | KDM4E (0.66) | NFE2L2TTRFDPSKDM4EALDH1A1 | |
| SCHEMBL9576505 | 0.72 | HCAR2 (0.47) | KDM4EALDH1A1MAPT | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411956 | 0.71 | FDPS (0.80) | NFE2L2TTRFDPSKDM4EALDH1A1 | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411955 | 0.71 | FDPS (0.80) | NFE2L2TTRFDPSKDM4EALDH1A1 | |
| SCHEMBL890347 | 0.71 | KDM4E (0.56) | NFE2L2TTRFDPSKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350314-B1 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO CO LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5315022-A | Sunscreen | SHISEIDO COMPANY LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| US-5093511-A | SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT | SHISEIDO COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |