Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730348 | 0.81 | KDM4E (0.66) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411956 | 0.77 | FDPS (0.80) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411955 | 0.77 | FDPS (0.80) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL8664544 | 0.75 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL889739 | 0.75 | KDM4E (0.66) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL6336593 | 0.75 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL6336601 | 0.75 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL12538642 | 0.75 | SMN1; SMN2 (0.69) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL10929433 | 0.75 | KDM4E (0.69) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL3003953 | 0.75 | NFE2L2 (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280848-A1 | COMPOSITION COMPRISING CHICORIC ACID AND/OR DERIVATIVES THEREOF | NESTEC S.A. (CH) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280848-A1 | COMPOSITION COMPRISING CHICORIC ACID AND/OR DERIVATIVES THEREOF | LCT, LDHA, SI | KDM4E 1347/4885SMN1; SMN2 3365/4885ALDH1A1 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.