SCHEMBL9126752

SCHEMBL9126752

O=[Si]([O-])[O-].O=[Si]([O-])[O-].O=[Si]([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17236 1.00
SCHEMBL9398161 1.00
SCHEMBL26885 1.00
SCHEMBL9701931 1.00
SCHEMBL6233000 0.94
Water SCHEMBL779387 0.94
SCHEMBL10667413 0.94
SCHEMBL10750832 0.94
SCHEMBL5850308 0.94
Water SCHEMBL10416553 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0189467-B1 NITRATION PROCESS FOR 2,3-DICHLORO-1,4-XYLENE RHONE-POULENC NEDERLAND B.V. (NL) 1989-03-22 EP claimed
US-5418250-A Hypotensive SMITHKLINE BEECHAM CORPORATION (US) 1995-05-23 US disclosed
EP-0537256-A1 DETERSIVE SYSTEM CONTAINING WATER SOLUBLE FILM ARTICLE. ECOLAB INC (US) 1993-04-21 EP disclosed
US-5185351-A Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma SMITHKLINE BEECHAM CORPORATION (US) 1993-02-09 US disclosed
WO-1992001037-A1 DETERSIVE SYSTEM CONTAINING WATER SOLUBLE FILM ARTICLE ECOLAB INC. (US) 1992-01-23 WO disclosed
EP-0189467-B1 NITRATION PROCESS FOR 2,3-DICHLORO-1,4-XYLENE RHONE-POULENC NEDERLAND B.V. (NL) 1989-03-22 EP disclosed
EP-0189467-B1 NITRATION PROCESS FOR 2,3-DICHLORO-1,4-XYLENE RHONE-POULENC NEDERLAND B.V. (NL) 1989-03-22 EP disclosed
EP-0189467-A1 NITRATION PROCESS FOR 2,3-DICHLORO-1,4-XYLENE. UNION CARBIDE CORP (US) 1986-08-06 EP disclosed
WO-1986000890-A1 NITRATION PROCESS FOR 2,3-DICHLORO-1,4-XYLENE UNION CARBIDE CORPORATION (US) 1986-02-13 WO disclosed