Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120611 | 0.84 | ALDH1A1 (0.43) | PTGS2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL31415662 | 0.81 | PTGS2 (0.44) | PTGS2PDE4BALDH1A1MAPTKDM4E | |
| SCHEMBL2902348 | 0.80 | KDM4E (0.69) | PTGS2PDE4BALDH1A1MAPTKDM4E | |
| SCHEMBL382979 | 0.79 | PTGS2 (0.41) | PTGS2PDE4BALDH1A1MAPTKDM4E | |
| SCHEMBL66141 | 0.79 | KDM4E (0.61) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL450776 | 0.77 | VDR (0.72) | PTGS2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL28448540 | 0.76 | KMT2A (0.46) | PTGS2PDE4BALDH1A1MAPTKDM4E | |
| SCHEMBL2902793 | 0.75 | KMT2A (0.45) | PTGS2PDE4BALDH1A1MAPTKDM4E | |
| SCHEMBL28737210 | 0.75 | PTGS2 (0.39) | PTGS2PDE4BALDH1A1MAPTKDM4E | |
| SCHEMBL450310 | 0.75 | KMT2A (0.69) | PTGS2ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449705-A | Silicon-containing polyamic acid derivative and photosensitive resin composition using it | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |