SCHEMBL913153

SCHEMBL913153

O=C(c1ccccc1)n1ccc(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.51
CRBN Q96SW2 3/20 0.50
TSHR P16473 1/20 0.50
RAB9A P51151 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
DDB1 Q16531 1/20 0.50
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
PKM P14618 1/20 0.46
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DUT P33316 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1468886 0.83 L3MBTL1 (0.47) TYMPCRBNL3MBTL1POLBHSD17B10
SCHEMBL2976955 0.79 CRBN (0.48) CRBNDDB1KDM4ELMNAPKM
SCHEMBL4712434 0.78 TSHR (0.54) TYMPTSHRRAB9AL3MBTL1KDM4E
SCHEMBL28132697 0.77 CRBN (0.47) TYMPCRBNDDB1KDM4ELMNA
SCHEMBL27581645 0.77 CRBN (0.50) CRBNDDB1LMNAPKMDUT
SCHEMBL10953746 0.77 CRBN (0.50) CRBNDDB1LMNAPKMDUT
SCHEMBL11560902 0.76 TSHR (0.47) TYMPTSHRRAB9AL3MBTL1KDM4E
SCHEMBL108176 0.76 CRBN (0.46) CRBNDDB1KDM4ELMNAPKM
SCHEMBL16057473 0.73 POLB (0.43) TYMPCRBNDDB1POLBHSD17B10
SCHEMBL7056290 0.73 CRBN (0.52) CRBNDDB1LMNAPKMDUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58198500-A None JP disclosed
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2026-04-16 US disclosed
US-20260069717-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNATX INC (US) 2026-03-12 US disclosed
CN-112105625-B Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same 赛诺菲 2024-12-31 CN disclosed
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2024-11-14 US disclosed
EP-4373935-A1 UNC13A ANTISENSE OLIGONUCLEOTIDES Acurastem, Inc. (US) 2024-05-29 EP disclosed
EP-4359532-A2 PIKFYVE ANTISENSE OLIGONUCLEOTIDES AcuraStem Incorporated (US) 2024-05-01 EP disclosed
WO-2024064854-A2 COMPOUNDS AND METHODS FOR REDUCING MECP2 EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2024-03-28 WO disclosed
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same SANOFI (FR) 2024-02-13 US disclosed
EP-4301766-A1 PURIFICATION METHODS FOR OLIGOMERIC COMPOUNDS Ionis Pharmaceuticals, Inc. (US) 2024-01-10 EP disclosed
WO-2006113204-A2 THYMIDINE DERIVATIVES FOR TREATMEMT OF KAPOSI'S SARCOMA THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-10-26 WO disclosed
EP-1701727-A1 DUTPASE INHIBITORS Medivir Aktiebolag (SE) 2006-09-20 EP disclosed
WO-2005097757-A2 NUCLEOSIDE DERIVATIVES AND THERAPEUTIC USE THEREOF REXAHN CORPORATION (US) 2005-10-20 WO disclosed
US-20050222185-A1 Nucleoside derivatives and therapeutic uses therof REXAHN CORPORATION (US) 2005-10-06 US disclosed
WO-2005065689-A1 DUTPASE INHIBITORS MEDIVIR AB (SE) 2005-07-21 WO disclosed
WO-2003018577-A1 ANTIVIRAL NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THE SAME POSTECH FOUNDATION (KR) 2003-03-06 WO disclosed
EP-0827498-A1 NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS Samjin Pharmaceutical Co., Ltd. (KR) 1998-03-11 EP disclosed
WO-1998005662-A1 CONFORMATIONALLY LOCKED NUCLEOSIDE ANALOGS AS ANTIHERPETIC AGENTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-02-12 WO disclosed
WO-1997030979-A1 NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS SAMJIN PHARMACEUTICAL CO., LTD. (KR) 1997-08-28 WO disclosed
JP-S58198500-A RIBONUCLEOSIDE SUBSTITUTED WITH 4-METHOXYBENZYL GROUP IN THE 2'-POSITION MITSUI TOATSU CHEM INC 1983-11-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same RNMT, RRM2B, RRM2 TYMP 138/4885CRBN 1552/4885TSHR 1805/4885
US-20050222185-A1 Nucleoside derivatives and therapeutic uses therof TYMP, NUDT1, HPRT1 TYMP 1/4885CRBN 3367/4885TSHR 3932/4885
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME NSUN2, NSUN3, SNRPA TYMP 511/4885CRBN 648/4885TSHR 1010/4885
US-20260069717-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF RNMT, RNGTT, NSUN2 TYMP 67/4885CRBN 3589/4885TSHR 3990/4885
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, NSUN2, ADAR TYMP 123/4885CRBN 1601/4885TSHR 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.