Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 10/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143042 | 0.75 | TOP2A (0.40) | PTK2KDM4E | |
| SCHEMBL11486604 | 0.74 | DRD2 (0.44) | LMNAKDM4EMAPT | |
| SCHEMBL9137776 | 0.74 | KDM4E (0.47) | LMNAKDM4E | |
| SCHEMBL5959482 | 0.71 | PGR (0.52) | LMNAKDM4EMAPT | |
| SCHEMBL9139762 | 0.69 | ALDH1A1 (0.40) | KDM4EMAPT | |
| SCHEMBL9140952 | 0.69 | POLL (0.33) | KDM4EMAPT | |
| SCHEMBL13021607 | 0.69 | MAOA (0.49) | KDM4EMAPTDYRK1ADYRK1B | |
| SCHEMBL11495734 | 0.68 | MAPT (0.46) | LMNAKDM4EMAPT | |
| SCHEMBL9140407 | 0.68 | ALDH1A1 (0.47) | KDM4EMAPT | |
| SCHEMBL9140565 | 0.68 | TXNRD1 (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428002-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0447506-B1 | PYRIMIDINE AND TRIAZINE DERIVATIVES WITH HERBICIDAL AND PLANT GROWTH REGULATING PROPERTIES | CIBA GEIGY AG (CH) | 1994-10-26 | — | — | EP | disclosed |
| US-5332717-A | Herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1991005781-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES WITH HERBICIDAL AND PLANT GROWTH REGULATING PROPERTIES | DR. R. MAAG AG (CH) | 1991-05-02 | — | — | WO | disclosed |