Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.44 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297186 | 0.76 | NISCH (0.40) | NISCHADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL8409961 | 0.73 | NOS3 (0.50) | NOS2MAOAMAOB | |
| SCHEMBL21339719 | 0.73 | NOS2 (0.49) | NOS2HTR1A | |
| SCHEMBL7597438 | 0.73 | GABRA1 (0.52) | ADRA1A | |
| SCHEMBL8775047 | 0.71 | GABRA1 (0.54) | ADRA1A | |
| SCHEMBL1199345 | 0.67 | NISCH (0.54) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL30389786 | 0.66 | PDK2 (0.36) | NOS2OPRM1 | |
| SCHEMBL11037136 | 0.66 | TAAR1 (0.46) | NISCHADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL28466461 | 0.66 | NISCH (0.45) | NISCHADRA2AADRA2BADRA2CNOS2 | |
| SCHEMBL2791953 | 0.66 | CNR2 (0.35) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663856-A1 | APPARATUS AND METHOD FOR MULTIPLE SIMULTANEOUS SYNTHESIS | WARNER-LAMBERT COMPANY (US) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008711-A1 | APPARATUS AND METHOD FOR MULTIPLE SIMULTANEOUS SYNTHESIS | WARNER-LAMBERT COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |