Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.47 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890233 | 0.74 | MAOA (0.69) | MAOBMAOACREBBPTNKS2 | |
| SCHEMBL10927781 | 0.72 | S1PR1 (0.57) | MAOBL3MBTL1FFAR1NPC1RAB9A | |
| SCHEMBL13760599 | 0.72 | ALDH1A1 (0.51) | MAOBL3MBTL1LTB4RLTB4R2NPC1 | |
| SCHEMBL5446276 | 0.72 | L3MBTL1 (0.53) | MAOBL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2848161 | 0.71 | MAOB (0.60) | MAOBL3MBTL1FFAR1LTB4RLTB4R2 | |
| SCHEMBL29593701 | 0.71 | MAOB (0.50) | MAOBL3MBTL1FFAR1NPC1RAB9A | |
| SCHEMBL21383069 | 0.70 | MAOB (0.51) | MAOBHIF1AL3MBTL1LTB4RLTB4R2 | |
| SCHEMBL853597 | 0.69 | LTA4H (0.64) | — | |
| SCHEMBL30176255 | 0.69 | LTA4H (0.64) | — | |
| SCHEMBL6664147 | 0.69 | ALDH1A1 (0.60) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420123-A | Dibenzodiazepine endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-05-30 | — | — | US | disclosed |