Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MDH2 | P40926 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 5/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853597 | 0.91 | LTA4H (0.64) | PPARGLTA4HPLA2G2AMEN1KMT2A | |
| SCHEMBL30176255 | 0.91 | LTA4H (0.64) | PPARGLTA4HPLA2G2AMEN1KMT2A | |
| SCHEMBL7123353 | 0.89 | PKM (0.62) | ALDH1A1HPGDMDH2SMN1; SMN2PPARG | |
| SCHEMBL4473938 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDMDH2SMN1; SMN2PPARG | |
| SCHEMBL9950019 | 0.86 | ALDH1A1 (0.62) | ALDH1A1HPGDMDH2SMN1; SMN2PPARG | |
| SCHEMBL14488753 | 0.82 | CTSV (0.52) | ALDH1A1HPGDSMN1; SMN2LTA4HPLA2G2A | |
| SCHEMBL14487863 | 0.82 | TRPM8 (0.46) | ALDH1A1HPGDMDH2SMN1; SMN2PPARG | |
| SCHEMBL30866124 | 0.81 | LTA4H (0.67) | ALDH1A1HPGDMDH2SMN1; SMN2PPARG | |
| SCHEMBL29186144 | 0.81 | LTA4H (0.67) | ALDH1A1HPGDMDH2SMN1; SMN2PPARG | |
| SCHEMBL2433763 | 0.81 | MDH2 (0.69) | ALDH1A1HPGDMDH2SMN1; SMN2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024939-A2 | LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR, AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |