Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.61 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.61 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918836 | 0.87 | ADORA3 (0.58) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL918127 | 0.86 | ADORA3 (0.55) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL6451793 | 0.82 | CYP3A4 (0.73) | ADORA3SLC29A1TSHRCYP3A4NFKB1 | |
| SCHEMBL3253858 | 0.82 | ADORA3 (0.81) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL9388463 | 0.82 | ADORA3 (0.81) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL1320875 | 0.82 | ADORA3 (0.64) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL27437734 | 0.81 | ADORA3 (0.76) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL20491589 | 0.81 | ADORA3 (0.78) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL918592 | 0.81 | DNPH1 (0.74) | ADORA3TP53SLC29A1TDP1TSHR | |
| SCHEMBL30395396 | 0.80 | DNPH1 (0.64) | ADORA3TP53SLC29A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252919-B2 | 2′-hydroxy-protected ribonucleoside derivative and production method thereof | KANEKA CORPORATION (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20110009609-A1 | 2'-HYDROXY-PROTECTED RIBONUCLEOSIDE DERIVATIVE AND PRODUCTION METHOD THEREOF | KANEKA CORPORATION (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2258709-A1 | 2'-HYDROXYL-PROTECTED RIBONUCLEOSIDE DERIVATIVE AND MANUFACTURING METHOD OF SAME | Kaneka Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009609-A1 | 2'-HYDROXY-PROTECTED RIBONUCLEOSIDE DERIVATIVE AND PRODUCTION METHOD THEREOF | RNASEL, RNASEH1, NUDT1 | ADORA3 480/4885TP53 3962/4885SLC29A1 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.