Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 12/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 12/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466444 | 0.81 | KMT2A (0.43) | ITGA4ITGB7BRD4BRD9ITGB1 | |
| SCHEMBL466423 | 0.80 | BRD4 (0.42) | ITGA4ITGB7BRD4BRD9ITGB1 | |
| SCHEMBL22016782 | 0.72 | ITGA4 (0.38) | ITGA4ITGB7BRD4BRD9KDM4E | |
| SCHEMBL23095063 | 0.72 | MAPT (0.50) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL22035249 | 0.71 | ITGA4 (0.49) | ITGA4ITGB7ITGB1 | |
| SCHEMBL8280366 | 0.71 | ITGA4 (0.54) | ITGA4ITGB7ITGB1ALDH1A1 | |
| SCHEMBL21835475 | 0.69 | MAPT (0.45) | ITGA4ITGB7MEN1KMT2AKDM4E | |
| SCHEMBL29384915 | 0.69 | MAPT (0.45) | ITGA4ITGB7MEN1KMT2AKDM4E | |
| SCHEMBL509614 | 0.68 | CRHR1 (0.41) | ITGA4ITGB7ITGB1ALDH1A1 | |
| SCHEMBL919619 | 0.67 | ITGA4 (0.49) | ITGA4ITGB7ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096534-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9096533-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-8962625-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8541414-B2 | Pyridazinone compound and use thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | KIJI TOSHIYUKI (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2405745-A1 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20110319266-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2187745-A2 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2187744-A2 | HERBICIDAL COMPOSITION COMPRISING A PYRIDAZINONE COMPOUND WITH A SPECIFIC HERBICIDE AND A SPECIFIC SAFENER | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-1996557-B1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2010-03-03 | — | — | EP | disclosed |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| WO-2009035145-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035151-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035146-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| EP-1996557-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | Sumitomo Chemical Company, Limited (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007119434-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319266-A1 | HERBICIDAL COMPOSITION | DDT, EGLN1, ELF3 | ITGA4 4364/4885ITGB7 4725/4885BRD4 3249/4885 |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | ITGA4 3367/4885ITGB7 3093/4885BRD4 1708/4885 |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | WEE1, WEE2, H1-3 | ITGA4 4301/4885ITGB7 4486/4885BRD4 1240/4885 |
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | ITGA4 1752/4885ITGB7 1518/4885BRD4 3219/4885 |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | ITGA4 3367/4885ITGB7 3093/4885BRD4 1708/4885 |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | ITGA4 3367/4885ITGB7 3093/4885BRD4 1708/4885 |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | PDXK, DDT, PLPBP | ITGA4 3910/4885ITGB7 3989/4885BRD4 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.