SCHEMBL9198399

SCHEMBL9198399

O=C(O)Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PYGM P11217 3/20 0.53
▸ SLC28A1 O00337 1/20 0.47
▸ SLC28A2 O43868 1/20 0.47
▸ SLC29A1 Q99808 1/20 0.47
▸ SLC28A3 Q9HAS3 1/20 0.47
▸ TK2 O00142 2/20 0.47
▸ DNPH1 O43598 1/20 0.44
▸ P2RY2 P41231 1/20 0.44
▸ CDK1 P06493 1/20 0.43
▸ CDA P32320 3/20 0.43
▸ HPGD P15428 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ PAX8 Q06710 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9198406 1.00 PYGM (0.53) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1071873 0.90 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1071869 0.90 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL18740738 0.90 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL157986 0.88 PYGM (0.65) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL157985 0.88 PYGM (0.65) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL11883660 0.88 PYGM (0.57) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30130603 0.87 PYGM (0.56) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL11877280 0.87 PYGM (0.56) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15810617 0.87 PYGM (0.49) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 — — CN claimed
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 — — EP claimed
CN-117750971-A Methods of treating or preventing autoimmune diseases 易姆赛斯股份公司 2024-03-22 — — CN claimed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 — — CN disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 — — US disclosed
US-12612658-B2 RNA replication using transcription polymerases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-04-28 — — US disclosed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 — — EP disclosed
US-12582609-B2 Cancer vaccines MODERNATX, INC. (US) 2026-03-24 — — US disclosed
US-20260071212-A1 GalNAc conjugated oligonucleotides for RNA editing KORRO BIO INC (US) 2026-03-12 — — US disclosed
US-20260071215-A1 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF UNIV JOHNS HOPKINS (US) 2026-03-12 — — US disclosed
EP-3752610-B1 POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDES ETHRIS GMBH (DE) 2026-01-28 — — EP disclosed
WO-2017066797-A1 TRINUCLEOTIDE MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066793-A1 MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066781-A1 MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066791-A1 SUGAR SUBSTITUTED MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066789-A1 MRNA CAP ANALOGS WITH MODIFIED SUGAR MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
US-5476931-A Reacting with a base in a mixed solvent containing alcohol RIKAGAKU KENKYUSHO (JP) 1995-12-19 — — US disclosed
EP-0311694-B1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION RIKAGAKU KENKYUSHO (JP) 1995-12-13 — — EP disclosed
US-5144018-A Antiviral Agents RIKAGAKU KENKYUSHO (JP) 1992-09-01 — — US disclosed
EP-0311694-A1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION RIKAGAKU KENKYUSHO (JP) 1989-04-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12582609-B2 Cancer vaccines RNMT, MICA, NSUN2 PYGM 4875/4885SLC28A1 2511/4885SLC28A2 2534/4885
US-20260071215-A1 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF UPF1, RBM26, RPRD2 PYGM 2646/4885SLC28A1 377/4885SLC28A2 212/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT PYGM 3599/4885SLC28A1 1985/4885SLC28A2 1854/4885
US-12612658-B2 RNA replication using transcription polymerases RNGTT, POLRMT, POLM PYGM 1875/4885SLC28A1 3216/4885SLC28A2 2858/4885
US-20260071212-A1 GalNAc conjugated oligonucleotides for RNA editing NSUN3, ADAR, TRMT1L PYGM 454/4885SLC28A1 386/4885SLC28A2 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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