SCHEMBL920529

SCHEMBL920529

[c]1ccc(Cc2cc3ccccc3o2)s1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LOXL2 Q9Y4K0 1/20 0.50
▸ AGXT P21549 1/20 0.46
▸ ADRA2A P08913 1/20 0.40
▸ HTR2B P41595 4/20 0.40
▸ HTR1A P08908 2/20 0.40
▸ CYP19A1 P11511 1/20 0.39
▸ SLC5A2 P31639 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ SLC6A4 P31645 1/20 0.36
▸ DRD2 P14416 2/20 0.35
▸ CYP2A6 P11509 2/20 0.35
▸ FLT3 P36888 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MGLL Q99685 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14075637 0.78 LOXL2 (0.69) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL30100825 0.73 LOXL2 (0.53) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL28921514 0.73 LOXL2 (0.53) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL7806512 0.72 LOXL2 (0.60) LOXL2AGXTHTR2BHTR1ACYP19A1
SCHEMBL1680581 0.71 LOXL2 (0.50) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL2861535 0.71 LOXL2 (0.50) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL2870978 0.71 LOXL2 (0.50) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL4904304 0.70 NPC1 (0.45) LOXL2ADRA2ACYP19A1SMN1; SMN2FLT3
SCHEMBL8909605 0.69 LOXL2 (0.51) LOXL2AGXTADRA2AHTR2BHTR1A
SCHEMBL10395999 0.69 LOXL2 (0.44) LOXL2AGXTADRA2AHTR2BHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 — — US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 — — EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 — — US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 — — EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX LOXL2 3752/4885AGXT 6/4885ADRA2A 4055/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 LOXL2 2606/4885AGXT 21/4885ADRA2A 4392/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 LOXL2 4268/4885AGXT 48/4885ADRA2A 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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