SCHEMBL920807

SCHEMBL920807

Fc1[c]cccc1Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
LTA4H P09960 1/20 0.42
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC6A4 P31645 5/20 0.41
SLC6A2 P23975 4/20 0.41
HTR1A P08908 3/20 0.41
SLC6A3 Q01959 3/20 0.41
HTR2A P28223 1/20 0.39
HRH1 P35367 1/20 0.39
CTNNB1 P35222 1/20 0.39
ALDH1A1 P00352 2/20 0.38
RIPK1 Q13546 1/20 0.38
HPGD P15428 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
KDM1A O60341 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919101 0.88 SLC6A2 (0.42) LMNAGAAKMT2ASLC6A4SLC6A2
SCHEMBL921197 0.83 CA12 (0.36) LMNASLC6A4SLC6A2HTR1ASLC6A3
SCHEMBL919270 0.83 MAPT (0.43) KMT2ASLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL919481 0.83 ALDH1A1 (0.47) LTA4HLMNAGAAKMT2ASLC6A4
SCHEMBL920606 0.83 SLC6A4 (0.42) LMNAKMT2ASLC6A4SLC6A2HTR1A
SCHEMBL921720 0.82 SLC6A4 (0.48) KMT2ASLC6A4SLC6A2HTR1ASLC6A3
SCHEMBL919708 0.81 SLC6A4 (0.34) SLC6A4SLC6A2HTR1ASLC6A3HTR2A
SCHEMBL920698 0.80 HTR1A (0.44) KMT2ASLC6A4SLC6A2HTR1ASLC6A3
SCHEMBL919267 0.79 SLC6A4 (0.46) LMNAGAAKMT2ASLC6A4MAPK1
SCHEMBL919283 0.79 MAPT (0.44) TSHRLMNAKMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1292556-A2 CATALYTIC DEHYDROXYLATION OF DIOLS AND POLYOLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2003-03-19 EP claimed
WO-2001098241-A2 CATALYTIC DEHYDROXYLATION OF DIOLS AND POLYOLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2001-12-27 WO claimed
EP-0058505-B1 PREPARATION OF ESTERS CONTAINING AN ALPHA-CYANO GROUP IN THE ALCOHOL PORTION OF THE ESTERS FMC Corporation (US) 1985-05-29 EP claimed
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
CN-101641012-A Agricultural composition for controlling or preventing plant diseases caused by plant pathogenic microbes SUMITOMO CHEMICAL CO JP 2010-02-03 CN disclosed
US-5985919-A INSECTICIDES AND FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-16 US disclosed
CN-1044661-C Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives HOECHST AG (DE) 1999-08-18 CN disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
EP-0249015-A1 Silane derivatives, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-16 EP disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed
EP-0191847-A4 ARTHROPODICIDES. COMMW SCIENT IND RES ORG (AU) 1987-01-20 EP disclosed
EP-0191847-A1 ARTHROPODICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1986-08-27 EP disclosed
WO-1986001501-A1 ARTHROPODICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1986-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX TSHR 4380/4885LTA4H 1920/4885LMNA 3240/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 TSHR 2588/4885LTA4H 3410/4885LMNA 4812/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 TSHR 2777/4885LTA4H 3981/4885LMNA 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.