Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216809 | 0.87 | NAAA (0.49) | NAAAALOX15HDAC1HDAC2CDK1 | |
| SCHEMBL9220337 | 0.86 | L3MBTL1 (0.49) | NAAAALOX15HDAC1HDAC2CDK1 | |
| SCHEMBL9218736 | 0.85 | NAAA (0.47) | NAAAALOX15EPHX1HDAC1HDAC2 | |
| SCHEMBL9212465 | 0.85 | HDAC1 (0.54) | NAAAALOX15EPHX1HDAC1HDAC2 | |
| SCHEMBL9217584 | 0.82 | NAAA (0.46) | NAAAALOX15EPHX1PTGS2NPC1 | |
| SCHEMBL9212386 | 0.80 | L3MBTL1 (0.52) | NAAAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL9431631 | 0.80 | L3MBTL1 (0.52) | NAAAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL9217430 | 0.79 | TBK1 (0.46) | NPC1RAB9ATBK1 | |
| SCHEMBL9430225 | 0.78 | NPC1 (0.50) | HDAC1HDAC2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9216012 | 0.78 | TP53 (0.55) | NAAAHDAC1HDAC2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |