Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | RORA | P35398 | 3/20 | 0.49 |
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | RORB | Q92753 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209339 | 0.79 | KDM4E (0.44) | ALDH1A1POLBKDM4EHPGDADORA3 | |
| SCHEMBL9218908 | 0.73 | PLK1 (0.46) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL9216799 | 0.72 | KDM4E (0.42) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL9217137 | 0.68 | ADORA3 (0.43) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL8755337 | 0.68 | KDM4E (0.62) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL9217657 | 0.67 | UTS2R (0.46) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL8755136 | 0.67 | KDM4E (0.66) | ALDH1A1POLBKDM4EHPGDLMNA | |
| SCHEMBL14141960 | 0.67 | RORA (1.00) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL9210569 | 0.67 | PGR (0.57) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL14141640 | 0.66 | PGR (0.68) | PGRRORARORCRORBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476544-B1 | Pyrazoloquinoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5192768-A | Antiinflammatory, hepatic insufficiency | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-03-09 | — | — | US | disclosed |
| EP-0476544-A1 | Pyrazoloquinoline derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |