Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068487 | 0.90 | CYP2A6 (0.56) | CYP2A6MEN1KMT2ARXFP1AKR1B1 | |
| SCHEMBL16178092 | 0.89 | HSP90AA1 (0.48) | CYP2A6MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL19871768 | 0.85 | ERN1 (0.46) | CYP2A6MEN1KMT2ARXFP1AKR1B1 | |
| SCHEMBL11181615 | 0.82 | ALDH1A1 (0.43) | CYP2A6MEN1KMT2ARXFP1AKR1B1 | |
| SCHEMBL1527465 | 0.82 | ALDH1A1 (0.64) | CYP2A6MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL31266523 | 0.82 | ALDH1A1 (0.64) | CYP2A6MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL268735 | 0.82 | ALDH1A1 (0.65) | CYP2A6AKR1B1ALDH1A1HSD17B10TSHR | |
| SCHEMBL29391827 | 0.82 | ALDH1A1 (0.65) | CYP2A6AKR1B1ALDH1A1HSD17B10TSHR | |
| SCHEMBL30186719 | 0.82 | ALDH1A1 (0.65) | CYP2A6AKR1B1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9765502 | 0.82 | ALDH1A1 (0.52) | CYP2A6AKR1B1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-10693077-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-10483468-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-19 | — | — | US | disclosed |
| US-10476006-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-12 | — | — | US | disclosed |
| US-10454039-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-22 | — | — | US | disclosed |
| US-10454039-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-22 | — | — | US | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| US-10431751-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-01 | — | — | US | disclosed |
| US-10424744-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-09-24 | — | — | US | disclosed |
| EP-0012988-A1 | Levorotatory or dextrorotatory enantiomers of 3-halocyproheptadines, process for their preparation and pharmaceutical composition thereof | MERCK & CO. INC. (US) | 1980-07-09 | — | — | EP | disclosed |
| US-4132796-A | Antipsychotic 3-trifluoromethylsulfinyl analogs of cyproheptadine | MERCK & CO., INC. (US) | 1979-01-02 | — | — | US | disclosed |
| US-4104398-A | 3-Lower alkoxycyproheptadines as serotonin inhibitors | MERCK & CO., INC. (US) | 1978-08-01 | — | — | US | disclosed |
| US-4048223-A | 3-Dimethylsulfamoyl-5-[amino(alkyl or alkylidene)]-5H-dibenzo [a,d]cycloheptenes | MERCK & CO., INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4031222-A | ANTIEXTRAPYRAMIDAL, ANTIPSYCHOTIC, ENANTIOMERS, TRANQUILIZERS, ANTICHOLINERGIC | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4031223-A | ANTIEXTRAPYRAMIDAL, ANTIPSYCHOTIC, ENANTIOMERS, TRANQUILIZERS, ANTICHOLINERGIC | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4020169-A | FROM ARYL IODIDE OR BROMIDE AND TRIFLUOROMETHYL THIO COPPER | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |
| US-3981917-A | Chemical compounds | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3981877-A | APPETITE STIMULANTS | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3978121-A | 5H Dibenzo[a,d]cycloheptene derivatives | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10424744-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | CYP2A6 518/4885MEN1 305/4885KMT2A 927/4885 |
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | ESRRA, REN, ESRRB | CYP2A6 632/4885MEN1 2448/4885KMT2A 2239/4885 |
| US-10693077-B2 | Compound and organic electronic device using the same | SOD1, SCO2, RCOR3 | CYP2A6 1142/4885MEN1 2385/4885KMT2A 1209/4885 |
| US-10431751-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | CYP2A6 518/4885MEN1 305/4885KMT2A 927/4885 |
| US-10476006-B2 | Compound and organic electronic device using the same | ESR1, AOC2, PIEZO1 | CYP2A6 112/4885MEN1 205/4885KMT2A 844/4885 |
| US-10454039-B2 | Compound and organic electronic device using the same | ORC3, AOX1, RCOR3 | CYP2A6 497/4885MEN1 2797/4885KMT2A 1422/4885 |
| US-10483468-B2 | Compound and organic electronic device using the same | ORC3, RBX1, CBX3 | CYP2A6 1506/4885MEN1 1725/4885KMT2A 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.