SCHEMBL921577

SCHEMBL921577

CC(C)CCOc1ccc[c]c1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
MCHR1 Q99705 1/20 0.42
IDO1 P14902 1/20 0.40
TLR8 Q9NR97 1/20 0.39
TDP1 Q9NUW8 3/20 0.39
POLB P06746 1/20 0.36
ESR1 P03372 1/20 0.35
MAPK1 P28482 1/20 0.35
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
EPHX2 P34913 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207844 0.83 ALDH1A1 (0.42) TLR8TDP1POLBMAPTSMN1; SMN2
SCHEMBL677455 0.81 HTT (0.46) HTTMCHR1IDO1TLR8TDP1
SCHEMBL920758 0.81 L3MBTL1 (0.40) HTTMCHR1TLR8TDP1POLB
SCHEMBL921028 0.79 CYP1A2 (0.49) MCHR1TLR8TDP1MAPTSMN1; SMN2
SCHEMBL14814872 0.79 L3MBTL1 (0.39) HTTTDP1POLBMAPTL3MBTL1
SCHEMBL920535 0.79 KDM4E (0.41) TDP1MAPK1TP53L3MBTL1KDM4E
SCHEMBL919613 0.78 L3MBTL1 (0.45) MCHR1TLR8TDP1MAPTL3MBTL1
SCHEMBL919820 0.78 L3MBTL1 (0.41) TDP1MAPK1MAPTSMN1; SMN2L3MBTL1
SCHEMBL921771 0.78 L3MBTL1 (0.45) TDP1POLBMAPK1MAPTSMN1; SMN2
SCHEMBL920555 0.77 KDM4E (0.35) TDP1MAPK1TP53MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX HTT 218/4885MCHR1 3910/4885IDO1 111/4885
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HTT 2561/4885MCHR1 4630/4885IDO1 675/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 HTT 450/4885MCHR1 985/4885IDO1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.