Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207476 | 0.91 | HTR1A (0.33) | HTR1AUTS2RMEN1KMT2A | |
| SCHEMBL9206684 | 0.90 | HTR1A (0.41) | LTA4HHTR1AUTS2RKDM4EMAPK1 | |
| SCHEMBL9216452 | 0.89 | MEN1 (0.36) | HTR1AMEN1KMT2A | |
| SCHEMBL9217178 | 0.89 | HCN4 (0.39) | HTR1AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9215793 | 0.88 | HTR1A (0.39) | LTA4HHTR1AUTS2RKDM4EMAPK1 | |
| SCHEMBL9207407 | 0.85 | HTR1A (0.37) | HTR1A | |
| SCHEMBL9216989 | 0.85 | HTR1A (0.36) | LTA4HHTR1AUTS2RKDM4EALDH1A1 | |
| SCHEMBL9216877 | 0.84 | ACHE (0.35) | HTR1AMEN1KMT2A | |
| SCHEMBL9206867 | 0.84 | MTNR1A (0.39) | HTR1AMEN1KMT2A | |
| SCHEMBL9213910 | 0.84 | HCN4 (0.40) | HTR1AKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |