Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216877 | 0.96 | ACHE (0.35) | MEN1KMT2AESR1ESR2MCHR1 | |
| SCHEMBL9206867 | 0.94 | MTNR1A (0.39) | MEN1KMT2AMCHR1HTR1ASLC6A4 | |
| SCHEMBL9205217 | 0.92 | HCN4 (0.40) | MEN1KMT2AHTR1ASLC6A4GAA | |
| SCHEMBL9205646 | 0.92 | MEN1 (0.40) | MEN1KMT2AMCHR1NPC1RAB9A | |
| SCHEMBL9215882 | 0.89 | LTA4H (0.32) | MEN1KMT2AHTR1A | |
| SCHEMBL9206684 | 0.88 | HTR1A (0.41) | MEN1KMT2AHTR1A | |
| SCHEMBL9216931 | 0.87 | ACHE (0.36) | MEN1KMT2AESR1ESR2HTR1A | |
| SCHEMBL9210183 | 0.87 | HCN4 (0.40) | HTR1ASLC6A4GAAMAPT | |
| SCHEMBL9206494 | 0.86 | MTNR1A (0.41) | MEN1KMT2AMCHR1HTR1ANPC1 | |
| SCHEMBL9213796 | 0.86 | MTNR1A (0.41) | MEN1KMT2AHTR1ASLC6A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |