SCHEMBL921637

SCHEMBL921637

Fc1[c]ccc(Oc2ccncc2)c1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LTA4H P09960 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDR P35968 2/20 0.31
MAPK14 Q16539 2/20 0.31
BRAF P15056 1/20 0.31
TNNI3K Q59H18 1/20 0.31
CYP3A4 P08684 1/20 0.31
MMP1 P03956 1/20 0.30
SCN9A Q15858 1/20 0.30
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920762 0.81 LTA4H (0.48) LTA4HTSHR
SCHEMBL919683 0.81 HSPB1 (0.40) S1PR2FFAR4LTA4HSCN9A
SCHEMBL920902 0.80 LMNA (0.61) FFAR4LMNATDP1LTA4H
SCHEMBL920492 0.78 TEAD4 (0.44) FFAR4TDP1
SCHEMBL21630325 0.78 MAPT (0.44) LMNALTA4HTSHRCYP3A4
SCHEMBL28575004 0.78 S1PR2 (0.34) S1PR2FFAR4LMNATDP1LTA4H
SCHEMBL21630265 0.78 LTA4H (0.34) LTA4H
SCHEMBL921863 0.78 LTA4H (0.45) TDP1LTA4H
SCHEMBL921457 0.78 MAOA (0.44) LTA4HSCN9A
SCHEMBL919758 0.77 VEGFA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2875014-A2 ANTI-MUCUS DRUGS AND USES THEREFOR Washington University (US) 2015-05-27 EP disclosed
WO-2014015056-A2 ANTI-MUCUS DRUGS AND USES THEREFOR WASHINGTON UNIVERSITY (US) 2014-01-23 WO disclosed
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 S1PR2 3401/4885FFAR4 4404/4885LMNA 4812/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 S1PR2 3922/4885FFAR4 4184/4885LMNA 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.