Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025431 | 0.81 | MEN1 (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9025568 | 0.80 | METAP2 (0.39) | KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL9032014 | 0.78 | MAPT (0.36) | NPC1 | |
| SCHEMBL9026040 | 0.78 | HTR2C (0.39) | ALDH1A1HPGD | |
| SCHEMBL9025458 | 0.74 | CCR2 (0.48) | CCR2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL9025606 | 0.73 | MGAM (0.39) | — | |
| SCHEMBL9219005 | 0.73 | GPR84 (0.36) | KDM4E | |
| SCHEMBL9037251 | 0.72 | CD274 (0.33) | HPGDSMN1; SMN2 | |
| SCHEMBL9025904 | 0.69 | — | — | |
| SCHEMBL9030876 | 0.68 | NPBWR1 (0.34) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |