SCHEMBL9222018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10336303	0.74	HTT (0.48)	CYP3A4KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL8897227	0.73	MAOA (0.50)	CYP3A4KDM4EHSD17B10CYP2D6CYP2C9
	SCHEMBL1713988	0.73	HTT (0.42)	NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
	SCHEMBL7754898	0.73	HTT (0.53)	CYP3A4KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL1301705	0.71	CYP3A4 (0.62)	CYP3A4TDP1KDM4EALDH1A1HSD17B10
	SCHEMBL3447032	0.70	MAOA (0.47)	CYP3A4KDM4EHSD17B10CYP2D6CYP2C9
	SCHEMBL7877813	0.68	SIGMAR1 (0.49)	CYP3A4TDP1KDM4EALDH1A1HSD17B10
	SCHEMBL14152660	0.68	KCNA3 (0.51)	CYP3A4KDM4EHSD17B10CYP2D6CYP2C9
	SCHEMBL29419951	0.67	NDUFS8 (0.70)	NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
	SCHEMBL8936325	0.65	MAOA (0.56)	ALOX15CYP3A4KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.