Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 3/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 5/20 | 0.32 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234544 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TDP1MAP2EGLN1PYGL | |
| SCHEMBL1822936 | 0.87 | EIF4A3 (0.40) | ALDH1A1TDP1EGLN1EIF4A3 | |
| SCHEMBL27340858 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TDP1MAP2EGLN1PYGL | |
| SCHEMBL9232962 | 0.76 | EGLN1 (0.39) | EGLN1EIF4A3 | |
| SCHEMBL9233312 | 0.76 | ALOX15 (0.39) | ALDH1A1TDP1MAPT | |
| SCHEMBL741404 | 0.76 | EIF4A3 (0.56) | ALDH1A1TDP1PYGLEIF4A3ALPL | |
| SCHEMBL112135 | 0.75 | GPR35 (0.55) | — | |
| SCHEMBL3414863 | 0.74 | KDM4E (0.58) | ALDH1A1TDP1PYGLMAPT | |
| SCHEMBL3412727 | 0.74 | F7 (0.58) | ALDH1A1PYGLMAPTF7F3 | |
| SCHEMBL3414920 | 0.74 | DAO (0.50) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655440-A2 | 1-Aminoethylindoles | F. HOFFMANN-LA ROCHE AG (CH) | 1995-05-31 | — | — | EP | disclosed |