Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232297 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TDP1EIF4A3MAP2EGLN1 | |
| SCHEMBL1822936 | 0.87 | EIF4A3 (0.40) | ALDH1A1TDP1EIF4A3EGLN1LMNA | |
| SCHEMBL9233312 | 0.81 | ALOX15 (0.39) | ALDH1A1TDP1LMNAKDM4EHPGD | |
| SCHEMBL27340858 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1EIF4A3MAP2EGLN1 | |
| SCHEMBL9232962 | 0.79 | EGLN1 (0.39) | EIF4A3EGLN1GRIK1GRIA1GRIA2 | |
| SCHEMBL3639230 | 0.76 | EIF4A3 (0.60) | ALDH1A1TDP1EIF4A3ALPLLMNA | |
| SCHEMBL112135 | 0.75 | GPR35 (0.55) | — | |
| SCHEMBL1822086 | 0.75 | ALOX15 (0.44) | ALDH1A1LMNAKDM4EHPGDCYP2C19 | |
| SCHEMBL3412727 | 0.74 | F7 (0.58) | ALDH1A1PYGLLMNAF7F3 | |
| SCHEMBL3414863 | 0.74 | KDM4E (0.58) | ALDH1A1TDP1PYGLLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655440-A2 | 1-Aminoethylindoles | F. HOFFMANN-LA ROCHE AG (CH) | 1995-05-31 | — | — | EP | disclosed |