Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232297 | 0.87 | ALDH1A1 (0.39) | EIF4A3ALDH1A1TDP1EGLN1 | |
| SCHEMBL9234544 | 0.87 | ALDH1A1 (0.39) | EIF4A3KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL9232962 | 0.84 | EGLN1 (0.39) | EIF4A3EGLN1 | |
| SCHEMBL112135 | 0.80 | GPR35 (0.55) | GPR35DAO | |
| SCHEMBL3414863 | 0.79 | KDM4E (0.58) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL3414920 | 0.79 | DAO (0.50) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL9234958 | 0.79 | ALDH1A1 (0.40) | EIF4A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL1833251 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL3381701 | 0.72 | HRH4 (0.43) | KDM4EEGLN1 | |
| SCHEMBL3412727 | 0.72 | F7 (0.58) | KDM4EALDH1A1LMNADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493844-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011054436-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |
| EP-0655440-A2 | 1-Aminoethylindoles | F. HOFFMANN-LA ROCHE AG (CH) | 1995-05-31 | — | — | EP | disclosed |