Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.64 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.58 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.58 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.58 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.58 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475449 | 0.82 | HSD11B1 (0.75) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9234066 | 0.81 | ALDH1A1 (0.46) | HSD11B1NAMPTCNR2ALDH1A1MAPT | |
| SCHEMBL9232561 | 0.81 | ABCC9 (0.60) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9228703 | 0.81 | HTR6 (0.54) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL13884294 | 0.80 | ALDH1A1 (0.55) | ABCC9ABCC8KCNJ11KCNJ8HTR6 | |
| Hydrochloric Acid SCHEMBL9231987 | 0.80 | HTR6 (0.52) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL28543840 | 0.78 | HSD11B1 (0.69) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9403464 | 0.77 | HSD11B1 (0.68) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL2034446 | 0.77 | HSD11B1 (0.68) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL516500 | 0.77 | HSD11B1 (0.67) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |