Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL11442758 | 0.92 | SIRT1 (0.41) | SIRT1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL11427398 | 0.89 | ALDH1A1 (0.46) | SIRT1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL11552435 | 0.85 | SLC6A2 (0.44) | SIRT1ALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL11430852 | 0.85 | MMP2 (0.60) | ALDH1A1KMT2AMEN1MMP2MMP9 | |
| SCHEMBL11442736 | 0.85 | SLC6A9 (0.45) | SIRT1ALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL11554666 | 0.83 | MMP2 (0.49) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| SCHEMBL11400372 | 0.81 | MMP2 (0.38) | SIRT1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL9235115 | 0.79 | SIRT1 (0.47) | SIRT1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL9858501 | 0.71 | CYP2C19 (0.55) | SIRT1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5050606 | 0.71 | ACP3 (0.47) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447371-A | Preparation method of 2-chloro-6- (phenylthio) phenylacetic acid | 博骥源（上海）生物医药有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117447371-A | Preparation method of 2-chloro-6- (phenylthio) phenylacetic acid | 博骥源（上海）生物医药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117447371-A | Preparation method of 2-chloro-6- (phenylthio) phenylacetic acid | 博骥源（上海）生物医药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117447371-A | Preparation method of 2-chloro-6- (phenylthio) phenylacetic acid | 博骥源（上海）生物医药有限公司 | 2024-01-26 | — | — | CN | disclosed |