SCHEMBL9243201

SCHEMBL9243201

NNC(=O)C(=O)NN.NNC(=O)c1cccc(C(=O)NN)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.48
MAPT P10636 4/20 0.48
CTSD P07339 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
MITF O75030 1/20 0.48
NCOA1 Q15788 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
ALDH1A1 P00352 7/20 0.47
P2RX7 Q99572 2/20 0.47
GFER P55789 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPK1 P28482 1/20 0.44
BLM P54132 2/20 0.43
MPO P05164 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7600310 0.93 MAPT (0.53) GAAMAPTCTSDMEN1KMT2A
SCHEMBL723254 0.83 TERT (0.61) GAAMAPTCTSDMEN1KMT2A
SCHEMBL32018464 0.83 TERT (0.61) GAAMAPTCTSDMEN1KMT2A
SCHEMBL2564032 0.81 MMP2 (0.64) GAAMAPTCTSDMEN1KMT2A
SCHEMBL7868556 0.79 ALDH1A1 (0.62) GAAMAPTCTSDMEN1KMT2A
SCHEMBL4915363 0.79 MAPT (0.46) GAAMAPTCTSDMEN1KMT2A
SCHEMBL3607272 0.79 KLKB1 (0.61) GAAMAPTCTSDMEN1KMT2A
SCHEMBL2722234 0.79 CA1 (0.50) GAAMAPTCTSDMEN1KMT2A
SCHEMBL239328 0.79 CTSD (0.63) GAAMAPTCTSDMEN1KMT2A
SCHEMBL30547074 0.79 CTSD (0.63) GAAMAPTCTSDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333660-B1 Stabilization systems for polyacetals CIBA GEIGY AG (CH) 1995-06-28 EP claimed
EP-0333660-B1 Stabilization systems for polyacetals CIBA GEIGY AG (CH) 1995-06-28 EP disclosed
US-3940365-A PHENOLIC ANTIOXIDANT AND AN UREA OR AN OXALIC ACID DIAMIDE OR AN AZODICARBOXYLIC AMIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-24 US disclosed