Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200726 | 0.79 | OPRD1 (0.42) | OPRM1OPRD1CES2CES1CA1 | |
| SCHEMBL9038594 | 0.78 | HTR2A (0.53) | OPRM1OPRD1OPRK1CES2CES1 | |
| SCHEMBL10460871 | 0.75 | OPRD1 (0.65) | OPRM1OPRD1OPRK1CES2CES1 | |
| Bromide SCHEMBL10461679 | 0.72 | OPRD1 (0.61) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9249498 | 0.71 | ALDH1A1 (0.40) | KMT2ACES2CES1L3MBTL1LMNA | |
| SCHEMBL8314573 | 0.69 | OPRD1 (0.58) | OPRM1OPRD1OPRK1CES2CES1 | |
| SCHEMBL2297101 | 0.63 | MGLL (0.58) | MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL2090365 | 0.62 | AKR1C3 (0.43) | GSK3B | |
| SCHEMBL9256562 | 0.61 | SMN1; SMN2 (0.40) | TSHRCYP3A4L3MBTL1HTTRAB9A | |
| SCHEMBL401165 | 0.61 | CES2 (0.46) | MEN1KMT2ACES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |