Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 4/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260202 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL9256883 | 0.79 | KDM4E (0.36) | KDM4EHPGDALDH1A1MASP2ATM | |
| SCHEMBL9254764 | 0.78 | EPHX1 (0.38) | SMN1; SMN2GLSMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9257621 | 0.77 | PDK1 (0.36) | MASP2 | |
| SCHEMBL9257116 | 0.76 | CSNK2A2 (0.42) | SMN1; SMN2KDM4EHPGDHSD17B10CSNK2A2 | |
| SCHEMBL9568160 | 0.74 | YAP1 (0.41) | SMN1; SMN2MAPK1L3MBTL1ALDH1A1MASP2 | |
| SCHEMBL9568161 | 0.73 | BCHE (0.46) | MASP2 | |
| SCHEMBL9257782 | 0.73 | CSNK2A2 (0.39) | SMN1; SMN2KDM4EHPGDHSD17B10GLS | |
| SCHEMBL7301104 | 0.73 | CASP1 (0.49) | KDM4EHPGDALDH1A1MASP2 | |
| SCHEMBL9248672 | 0.71 | PTGER4 (0.40) | SMN1; SMN2KDM4EHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |