Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253457 | 0.83 | PRSS1 (0.41) | MAPK1ALDH1A1LMNARAB9A | |
| SCHEMBL9260202 | 0.83 | SMN1; SMN2 (0.39) | GLSMAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL9259284 | 0.78 | PDK1 (0.35) | EPHX1MEN1KMT2AMASP2 | |
| SCHEMBL9250720 | 0.78 | SMN1; SMN2 (0.39) | GLSMAPK1L3MBTL1SMN1; SMN2MASP2 | |
| SCHEMBL9257782 | 0.73 | CSNK2A2 (0.39) | GLSKMT2ASMN1; SMN2HDAC6RAB9A | |
| SCHEMBL7301568 | 0.72 | ITGB3 (0.47) | EPHX1KMT2ASMN1; SMN2MASP2ALDH1A1 | |
| SCHEMBL9245964 | 0.72 | CYP1A2 (0.37) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7309683 | 0.72 | ITGB3 (0.48) | EPHX1KMT2ASMN1; SMN2MASP2ALDH1A1 | |
| SCHEMBL9257665 | 0.70 | EDNRB (0.36) | EPHX1MAPK1MEN1KMT2AMASP2 | |
| SCHEMBL9568134 | 0.69 | YAP1 (0.39) | EPHX1KMT2ASMN1; SMN2MASP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |