Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253427 | 0.91 | OPRD1 (0.42) | OPRD1OPRL1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9253418 | 0.86 | OPRL1 (0.40) | OPRD1OPRL1OPRM1SLC6A9OPRK1 | |
| SCHEMBL9256532 | 0.84 | SIGMAR1 (0.38) | OPRD1OPRL1OPRM1OPRK1CHRM1 | |
| SCHEMBL9256528 | 0.78 | DGKA (0.34) | OPRD1OPRL1OPRM1OPRK1CYP3A4 | |
| SCHEMBL13955139 | 0.72 | OPRD1 (0.50) | OPRD1OPRL1OPRM1SLC6A9OPRK1 | |
| SCHEMBL4499828 | 0.71 | SIGMAR1 (0.52) | OPRD1OPRL1OPRM1SLC6A9OPRK1 | |
| SCHEMBL16226345 | 0.70 | OPRD1 (0.48) | OPRD1OPRL1OPRM1SLC6A9OPRK1 | |
| SCHEMBL16227065 | 0.70 | OPRD1 (0.48) | OPRD1OPRL1OPRM1SLC6A9OPRK1 | |
| SCHEMBL13163119 | 0.69 | OPRM1 (0.51) | OPRD1OPRL1OPRM1SLC6A9OPRK1 | |
| SCHEMBL21787342 | 0.69 | OPRM1 (0.51) | OPRD1OPRL1OPRM1SLC6A9OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |