Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 8/20 | 0.46 |
| ▸ | SPR | P35270 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262291 | 0.87 | GRIN1 (0.38) | SCD5SPRRAB9ANPC1ALDH1A1 | |
| SCHEMBL9253316 | 0.84 | LTB4R (0.56) | SPRMGLL | |
| SCHEMBL9257657 | 0.83 | HPGD (0.47) | RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9261899 | 0.79 | ALDH1A1 (0.55) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9254577 | 0.79 | SMN1; SMN2 (0.51) | CA12CA2CA9NPC1KMT2A | |
| SCHEMBL9261873 | 0.77 | MEN1 (0.53) | HSD11B1KMT2AALDH1A1 | |
| SCHEMBL9261971 | 0.76 | HSD11B1 (0.56) | HSD11B1MGLLALDH1A1 | |
| SCHEMBL9261138 | 0.76 | DRD2 (0.51) | KMT2A | |
| SCHEMBL9257855 | 0.75 | KDM4E (0.50) | KMT2AMGLLALDH1A1L3MBTL1 | |
| SCHEMBL9256417 | 0.74 | CA12 (0.43) | HSD11B1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |