Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257607 | 0.84 | ALDH1A1 (0.47) | HTR1APRMT6KDRCYP2E1CYP2A6 | |
| SCHEMBL9255957 | 0.84 | HTR1A (0.40) | HTR1APRMT6P2RX3KDRCYP2E1 | |
| SCHEMBL9256741 | 0.83 | LMNA (0.40) | PRMT6SLC6A9HSD17B1HSD17B2LTB4R | |
| SCHEMBL9259713 | 0.82 | LMNA (0.50) | HTR1APRMT6P2RX3TSHRMAPK1 | |
| SCHEMBL9169905 | 0.78 | TSHR (0.42) | HTR1APRMT6P2RX3TSHRMAPK1 | |
| SCHEMBL30963937 | 0.74 | RXRA (0.51) | PRMT6CYP2E1CYP2A6CYP2B6GAK | |
| SCHEMBL14408934 | 0.74 | ALDH1A1 (0.57) | HTR1AALDH1A1RECQL | |
| SCHEMBL12251044 | 0.73 | PRMT6 (0.47) | HTR1APRMT6KDRCYP2E1CYP2A6 | |
| SCHEMBL9258419 | 0.73 | P2RX3 (0.44) | HTR1APRMT6P2RX3SLC6A9MC4R | |
| SCHEMBL9258748 | 0.72 | PRMT6 (0.43) | HTR1APRMT6P2RX3KDRCYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |