Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258312 | 0.86 | ADORA1 (0.38) | HPGDKDM4EALDH1A1CYP3A4KMT2A | |
| SCHEMBL9261260 | 0.79 | GABRA1 (0.52) | TRPM2HPGDKDM4ECYP3A4LMNA | |
| SCHEMBL9257774 | 0.75 | ADORA3 (0.43) | KDM4EALDH1A1FAAH | |
| SCHEMBL9256941 | 0.75 | LMNA (0.46) | TRPM2HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9416617 | 0.74 | ADORA1 (0.39) | HPGDKDM4EALDH1A1CYP3A4LMNA | |
| SCHEMBL9264825 | 0.74 | LMNA (0.41) | TRPM2HPGDKDM4EALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9260218 | 0.74 | ADORA1 (0.38) | HPGDKDM4EALDH1A1CYP3A4LMNA | |
| SCHEMBL8864498 | 0.73 | ADORA2B (0.36) | TRPM2HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9257773 | 0.72 | ADORA2B (0.37) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9264420 | 0.71 | CXCR3 (0.39) | HPGDKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |