SCHEMBL9258172

SCHEMBL9258172

CCN(C)C(=O)n1cc(Cl)c(Sc2c(C)cccc2OC)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 2/20 0.35
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CREBBP Q92793 1/20 0.32
MAPT P10636 5/20 0.31
ALDH1A1 P00352 4/20 0.31
LMNA P02545 3/20 0.31
KDM4E B2RXH2 2/20 0.31
HTT P42858 2/20 0.31
NPSR1 Q6W5P4 3/20 0.31
USP2 O75604 1/20 0.31
GLA P06280 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
APLNR P35414 1/20 0.31
MAPK1 P28482 1/20 0.30
GFER P55789 1/20 0.30
GRIN2B Q13224 2/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9258315 0.91 KDM4E (0.35) KMT2AMEN1GAAL3MBTL1CREBBP
SCHEMBL9266727 0.90 APLNR (0.34) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL9259255 0.89 GAA (0.34) RORCKMT2AMEN1GAAL3MBTL1
SCHEMBL9265196 0.87 CYP1A2 (0.33) KMT2AMEN1GAAKDM4ENPSR1
SCHEMBL9268087 0.87 NPSR1 (0.34) GAANPSR1APLNR
SCHEMBL9269040 0.80 RORC (0.34) RORCL3MBTL1MAPTALDH1A1LMNA
SCHEMBL9266414 0.78 LMNA (0.38) RORCMAPTLMNANPSR1SMN1; SMN2
SCHEMBL9266791 0.78 ALDH1A1 (0.33) KMT2AMEN1GAAL3MBTL1CREBBP
SCHEMBL8782865 0.77 AR (0.40) GAAMAPTALDH1A1LMNAKDM4E
SCHEMBL8783055 0.77 MEN1 (0.32) KMT2AMEN1GAAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed