Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268087 | 0.96 | NPSR1 (0.34) | NPSR1CRHR1APAF1APLNRGAA | |
| SCHEMBL9258315 | 0.94 | KDM4E (0.35) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL9258172 | 0.87 | RORC (0.35) | KDM4ENPSR1USP2GLAAPLNR | |
| SCHEMBL9266727 | 0.86 | APLNR (0.34) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL9259255 | 0.85 | GAA (0.34) | CYP1A2CYP2C19KDM4ENPSR1MEN1 | |
| SCHEMBL9269040 | 0.84 | RORC (0.34) | NPSR1TSPO | |
| SCHEMBL9266414 | 0.82 | LMNA (0.38) | NPSR1TSPO | |
| SCHEMBL9266791 | 0.82 | ALDH1A1 (0.33) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL9263890 | 0.82 | RORC (0.35) | KDM4EGAATSPO | |
| SCHEMBL8782463 | 0.81 | RORC (0.32) | CYP3A4NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424279-A | Useful for rice crops | SANKYO COMPANY, LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493925-A1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-07-08 | — | — | EP | disclosed |