SCHEMBL9259255

SCHEMBL9259255

COc1cccc(C)c1Sc1nn(C(=O)N(C)C)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.34
RORC P51449 2/20 0.34
ALDH1A1 P00352 5/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.33
HTT P42858 2/20 0.33
P2RX7 Q99572 2/20 0.32
GRIN2B Q13224 1/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.31
NPSR1 Q6W5P4 3/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CACNB4 O00305 1/20 0.31
CACNA1A O00555 1/20 0.31
CACNA1G O43497 1/20 0.31
CACNG3 O60359 1/20 0.31
CACNA1F O60840 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9258172 0.89 RORC (0.35) GAARORCALDH1A1MAPTKDM4E
SCHEMBL9258315 0.88 KDM4E (0.35) GAAALDH1A1MAPTKDM4ELMNA
SCHEMBL9268087 0.86 NPSR1 (0.34) GAANPSR1
SCHEMBL9266727 0.86 APLNR (0.34) ALDH1A1MAPTKDM4ELMNAKMT2A
SCHEMBL9265196 0.85 CYP1A2 (0.33) GAAKDM4EKMT2ANPSR1MEN1
SCHEMBL9270186 0.79 RORC (0.42) GAARORCMAPTKDM4EGRIN2B
SCHEMBL9269040 0.77 RORC (0.34) RORCALDH1A1MAPTLMNAP2RX7
SCHEMBL9266791 0.75 ALDH1A1 (0.33) GAAALDH1A1MAPTKDM4ELMNA
SCHEMBL9266414 0.75 LMNA (0.38) RORCMAPTLMNAP2RX7SMN1; SMN2
SCHEMBL8782310 0.75 NR3C1 (0.34) GAARORCALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed