SCHEMBL9258315

SCHEMBL9258315

CCN(CC)C(=O)n1cc(Cl)c(Sc2c(C)cccc2OC)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
NPSR1 Q6W5P4 3/20 0.33
CNR1 P21554 1/20 0.33
USP2 O75604 1/20 0.33
GLA P06280 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 2/20 0.33
RECQL P46063 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CREBBP Q92793 1/20 0.32
ALDH1A1 P00352 4/20 0.32
LMNA P02545 4/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9265196 0.94 CYP1A2 (0.33) KDM4ENPSR1CNR1USP2GLA
SCHEMBL9268087 0.92 NPSR1 (0.34) NPSR1GAAHSD17B10APLNR
SCHEMBL9258172 0.91 RORC (0.35) KDM4ENPSR1USP2GLAMEN1
SCHEMBL9269040 0.90 RORC (0.34) NPSR1L3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL9259255 0.88 GAA (0.34) KDM4ENPSR1MEN1KMT2AGAA
SCHEMBL9266414 0.88 LMNA (0.38) NPSR1LMNASMN1; SMN2MAPT
SCHEMBL9266791 0.88 ALDH1A1 (0.33) KDM4ENPSR1USP2GLAMEN1
SCHEMBL8782463 0.86 RORC (0.32) NPSR1MEN1KMT2AALDH1A1LMNA
SCHEMBL8782865 0.86 AR (0.40) KDM4ENPSR1GAARECQLALDH1A1
SCHEMBL9266727 0.85 APLNR (0.34) KDM4EMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed