Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257774 | 0.88 | ADORA3 (0.43) | ADORA1ADORA2BKDM4EADORA3ALDH1A1 | |
| SCHEMBL9416617 | 0.88 | ADORA1 (0.39) | ADORA1ADORA2BHPGDPOLBTHRB | |
| Hydrochloric Acid SCHEMBL9260218 | 0.87 | ADORA1 (0.38) | ADORA1ADORA2BHPGDPOLBTHRB | |
| SCHEMBL9258551 | 0.86 | TRPM2 (0.37) | KMT2AHPGDPOLBKDM4ELMNA | |
| SCHEMBL9264420 | 0.84 | CXCR3 (0.39) | ADORA1KMT2AHPGDPOLBKDM4E | |
| SCHEMBL9257773 | 0.83 | ADORA2B (0.37) | ADORA1ADORA2BKMT2AHPGDKDM4E | |
| SCHEMBL9263544 | 0.81 | HPGD (0.40) | ADORA1ADORA2BKMT2AHPGDKDM4E | |
| SCHEMBL9261214 | 0.81 | ADORA2B (0.41) | ADORA1ADORA2BKMT2AHPGDKDM4E | |
| SCHEMBL9263087 | 0.76 | GABRA1 (0.54) | ADORA1ADORA2BHPGDPOLBKDM4E | |
| SCHEMBL9261373 | 0.72 | LMNA (0.47) | ADORA1ADORA2BKMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |