Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 6/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926644 | 0.90 | NPSR1 (0.50) | NPSR1ALDH1A1LMNAPTGER3GAA | |
| SCHEMBL926563 | 0.88 | NPSR1 (0.48) | NPSR1ALDH1A1LMNAPTGER3GAA | |
| SCHEMBL926444 | 0.85 | HSD11B1 (0.50) | NPSR1ALDH1A1LMNAPTGER3ESR1 | |
| SCHEMBL8380984 | 0.77 | ALDH1A1 (0.53) | NPSR1ALDH1A1LMNAGAAL3MBTL1 | |
| SCHEMBL644252 | 0.77 | ALDH1A1 (0.53) | NPSR1ALDH1A1LMNAGAAL3MBTL1 | |
| SCHEMBL644486 | 0.76 | ALDH1A1 (0.52) | NPSR1ALDH1A1LMNAGAAL3MBTL1 | |
| SCHEMBL927537 | 0.76 | MMP8 (0.44) | NPSR1ALDH1A1PTGER3MEN1MAPT | |
| SCHEMBL4840665 | 0.75 | KDM2B (0.44) | NPSR1ALDH1A1LMNAPTGER3MCL1 | |
| SCHEMBL3591921 | 0.74 | LMNA (0.50) | NPSR1ALDH1A1LMNAL3MBTL1ESR1 | |
| SCHEMBL926085 | 0.74 | LMNA (0.50) | NPSR1ALDH1A1LMNAL3MBTL1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872021-B2 | LXR receptor modulators | LABORATORIES FOURNIER S.A. (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20070099960-A1 | LXR receptor modulators | LABORATOIRES FOURNIER S.A. (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099960-A1 | LXR receptor modulators | NR1H2, NR1H3, PPARD | NPSR1 297/4885ALDH1A1 2845/4885LMNA 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.