Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | PDE8A | O60658 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28646392 | 0.98 | NUDT1 (0.47) | NUDT1PARP1METAP1METAP2DAO | |
| SCHEMBL11129386 | 0.73 | ALDH1A1 (0.57) | NUDT1MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL1624786 | 0.72 | NUDT1 (0.48) | NUDT1PARP1METAP1METAP2DAO | |
| SCHEMBL37862 | 0.71 | ALDH1A1 (0.59) | NUDT1MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL29396007 | 0.71 | ALDH1A1 (0.59) | NUDT1MAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL26669218 | 0.70 | ALDH1A1 (0.47) | PARP1METAP1METAP2DAOMAPKAPK2 | |
| SCHEMBL2026047 | 0.69 | METAP2 (0.40) | METAP1METAP2MAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL31042178 | 0.69 | DAO (0.53) | PARP1DAOPDE5AATAD2KDM4E | |
| SCHEMBL323981 | 0.69 | NUDT1 (0.60) | NUDT1METAP1METAP2FGFR1FLT1 | |
| Hydrochloric Acid SCHEMBL20597399 | 0.69 | ALDH1A1 (0.57) | NUDT1MAPKAPK2RPS6KA3CSNK2A1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512037-B | Pyridopyrazinone ionic compound and preparation method and application thereof | 华南农业大学 | 2022-12-09 | — | — | CN | claimed |
| CN-113248493-B | Fluorescent agent and method for rapidly and visually detecting carbamate pesticide residues | 广州汇标检测技术中心 | 2022-03-25 | — | — | CN | claimed |
| CN-113512037-A | Pyridopyrazinone ionic compound and preparation method and application thereof | 华南农业大学 | 2021-10-19 | — | — | CN | claimed |
| CN-113248493-A | Fluorescent agent and method for rapidly and visually detecting carbamate pesticide residues | 广州汇标检测技术中心 | 2021-08-13 | — | — | CN | claimed |
| EP-2091951-A2 | PYRIDO[2,3-B]PYRAZINE AND[1,8]-NAPHTYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2007130468-A2 | PYRIDO [2, 3-B] PYRAZINE AND [1, 8] -NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2007-11-15 | — | — | WO | claimed |
| JP-2007522200-A | — | — | 2007-08-09 | — | — | JP | claimed |
| EP-1718311-A1 | THERAPEUTIC COMBINATIONS OF ATYPICAL ANTIPSYCHOTICS WITH CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | Pfizer Products Incorporated (US) | 2006-11-08 | — | — | EP | claimed |
| WO-2005079807-A1 | THERAPEUTIC COMBINATIONS OF ATYPICAL ANTIPSYCHOTICS WITH CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-20020156089-A1 | Use of CRF antagonists and related compositions | PFIZER INC. | 2002-10-24 | — | — | US | claimed |
| US-6465465-B1 | PHOSPHODIESTERASE INHIBITORS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-10-15 | — | — | US | claimed |
| US-20020147199-A1 | PROCESS FOR THE TREATMENT OF ERECTILE DYSFUNCTION AND PRODUCT THEREFOR | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-10-10 | — | — | US | claimed |
| EP-0736532-B1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA MEDICA AG (DE) | 2002-05-15 | — | — | EP | claimed |
| EP-1097709-A2 | Use of corticotropin releasing factor antagonists for treating syndrome X | Pfizer Products Inc. (US) | 2001-05-09 | — | — | EP | claimed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | claimed |
| EP-0736532-A1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1996-10-09 | — | — | EP | claimed |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-20250171440-A1 | WRN INHIBITORS | NIMBUS WADJET, INC. | 2025-05-29 | — | — | US | disclosed |
| US-4988705-A | Antiallergens and -inflammatory agents; hypotensive agents immunological suppression; hyperproliferative skin disorders such as psoriasis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| US-4810708-A | ANTIALLERGY, IMMUNOSUPPRESSIVE | SCHERING CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171440-A1 | WRN INHIBITORS | WRN, BLM, RECQL | NUDT1 849/4885PARP1 146/4885METAP1 3706/4885 |
| US-20020156089-A1 | Use of CRF antagonists and related compositions | CRH, CRHR1, CRHR2 | NUDT1 4564/4885PARP1 4840/4885METAP1 1953/4885 |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | NUDT1 3904/4885PARP1 1538/4885METAP1 3926/4885 |
| US-20020147199-A1 | PROCESS FOR THE TREATMENT OF ERECTILE DYSFUNCTION AND PRODUCT THEREFOR | PDE5A, PDE3A, PDE3B | NUDT1 726/4885PARP1 1283/4885METAP1 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.