Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789812 | 0.77 | ALDH1A1 (0.41) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28000779 | 0.77 | ADRB1 (0.40) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL29958355 | 0.77 | — | — | |
| SCHEMBL9276285 | 0.77 | MGLL (0.37) | — | |
| SCHEMBL1238592 | 0.77 | MGLL (0.37) | — | |
| SCHEMBL28406341 | 0.77 | GAA (0.36) | GAAKDM4EMEN1KMT2AHTT | |
| SCHEMBL3319952 | 0.74 | HSD17B10 (0.42) | KDM4EMEN1KMT2ATP53ALOX15 | |
| SCHEMBL9588021 | 0.74 | NPC1 (0.49) | KEAP1GAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5314044 | 0.73 | KDM4E (0.37) | KDM4EKMT2AHTTALOX15SMN1; SMN2 | |
| SCHEMBL28211992 | 0.73 | FAAH (0.42) | CYP3A4ALOX15ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656004-A1 | DUAL FUNCTIONAL ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE AGENTS | CYTOMED, INC. (US) | 1995-06-07 | — | — | EP | disclosed |