Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468542 | 0.79 | PLA2G2A (0.44) | ALDH1A1ALDH2KDM4E | |
| SCHEMBL4939278 | 0.75 | ADRA1A (0.47) | ALOX15HSD17B10ALDH1A1TET2KDM4E | |
| SCHEMBL8550074 | 0.74 | EPHX1 (0.48) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8549199 | 0.72 | KEAP1 (0.37) | ALOX15HSD17B10TET2KMT2A | |
| SCHEMBL1840501 | 0.72 | TGFBR1 (0.37) | ALOX15HSD17B10ALDH1A1TET2KDM4E | |
| SCHEMBL6253985 | 0.72 | HDAC3 (0.42) | KMT2A | |
| SCHEMBL2190702 | 0.71 | GRIK1 (0.35) | ALOX15HSD17B10TET2TDP1 | |
| SCHEMBL636745 | 0.71 | ALOX15 (0.35) | ALOX15HSD17B10TET2MEN1KMT2A | |
| SCHEMBL4596397 | 0.71 | ECE1 (0.39) | ALOX15HSD17B10ALDH1A1TET2MEN1 | |
| SCHEMBL336883 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379462-B1 | Vinylic macromers containing perfluoropolyalkylether and polyalkylether segments, polymers, copolymers and ophthalmic devices made therefrom | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | claimed |