Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 7/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284587 | 0.72 | HTR7 (0.50) | PARP1HTR6MAPTCYP2C19 | |
| SCHEMBL9283302 | 0.71 | HTR2C (0.50) | HTR1ASLC6A2SLC6A4PARP1 | |
| SCHEMBL6933646 | 0.71 | LTB4R (0.52) | PARP1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23259451 | 0.68 | LRRK2 (0.62) | HTR1ASLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL7238059 | 0.68 | MEN1 (0.53) | MAPK14CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9283309 | 0.68 | DRD2 (0.52) | HTR1APARP1HTR6CYP2C19ALDH1A1 | |
| SCHEMBL19704875 | 0.68 | SMN1; SMN2 (0.49) | MAPK14MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL27202066 | 0.68 | ALDH1A1 (0.51) | SLC6A4PARP1HTR6ALDH1A1 | |
| SCHEMBL11091056 | 0.67 | MAOB (0.46) | SLC6A4PARP1EGFR | |
| SCHEMBL11088706 | 0.67 | PARP1 (0.66) | HTR1ASLC6A2SLC6A4SLC6A3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067561-A2 | Piperazine derivatives and processes for producing them | KOWA COMPANY, LTD. (JP) | 1982-12-22 | — | — | EP | disclosed |