SCHEMBL9293295

SCHEMBL9293295

COc1cc(Br)cc(-c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2E1 P05181 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C8 P10632 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2A6 P11509 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP4B1 P13584 1/20 0.55
CYP2B6 P20813 1/20 0.55
CYP3A5 P20815 1/20 0.55
CYP2A7 P20853 1/20 0.55
CYP3A7 P24462 1/20 0.55
CYP2F1 P24903 1/20 0.55
CYP2C18 P33260 1/20 0.55
CYP2C19 P33261 1/20 0.55
CYP2J2 P51589 1/20 0.55
CYP4F2 P78329 1/20 0.55
CYP4F8 P98187 1/20 0.55
CYP4A11 Q02928 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15641765 0.87 CYP1A1 (0.50) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL8987283 0.85 CYP1A1 (0.74) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL2407878 0.85 CYP1A1 (0.74) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL27404494 0.83 SLC6A2 (0.51) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL26498639 0.81 CYP1A1 (0.83) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL26498734 0.81 CYP1A1 (0.83) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL26498789 0.81 CYP1A1 (0.83) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL1710738 0.79 CYP1A1 (0.50) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL45718 0.78 ALDH1A1 (0.60) CYP1A2CYP3A4SLC6A2SLC6A4NPC1
SCHEMBL1562747 0.78 ALDH1A1 (0.60) CYP1A2CYP3A4SLC6A2SLC6A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 EP disclosed
US-12018037-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-06-25 US disclosed
US-12018037-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-06-25 US disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed
EP-3416956-B1 METHYLAMINE DERIVATIVES AS LYSYL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER THE INSTITUTE OF CANCER RES ROYAL CANCER HOSPITAL (GB) 2024-04-10 EP disclosed
US-11608330-B2 Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2023-03-21 US disclosed
US-20220372028-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2022-11-24 US disclosed
CN-109311839-B Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer 癌症研究协会皇家癌症医院 2021-11-02 CN disclosed
US-10995088-B2 Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2021-05-04 US disclosed
US-20190152966-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2019-05-23 US disclosed
EP-3416956-A1 METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER The Institute of Cancer Research : The Royal Cancer Hospital (GB) 2018-12-26 EP disclosed
WO-2017141049-A1 METHYLAMINE DERIVATIVES AS LYSYSL OXIDASE INHIBITORS FOR THE TREATMENT OF CANCER THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2017-08-24 WO disclosed
US-5350846-A Antibiotics MERCK & CO., INC. (US) 1994-09-27 US disclosed
US-5208329-A Antibacterial agents MERCK & CO., INC. (US) 1993-05-04 US disclosed
US-5182385-A Chemical intermediates for bactericides MERCK & CO., INC. (US) 1993-01-26 US disclosed
EP-0467434-A1 2-Biphenyl-carbapenem antibacterial agents MERCK & CO. INC. (US) 1992-01-22 EP disclosed
EP-0464900-A2 2-Biphenyl-carbapenems MERCK & CO. INC. (US) 1992-01-08 EP disclosed
US-5025006-A Carbapenicillin antibiotics MERCK & CO., INC. (US) 1991-06-18 US disclosed
US-5011832-A 2-biphenyl-carbapenem antibacterial agents MERCK & CO., INC. (US) 1991-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152966-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer LOXL1, LOXL3, LOXL2 CYP1A1 1061/4885CYP1A2 1416/4885CYP2E1 1271/4885
US-20220372028-A1 Methylamine Derivatives as Lysysl Oxidase Inhibitors for the Treatment of Cancer LOXL1, LOXL3, LOXL2 CYP1A1 1061/4885CYP1A2 1416/4885CYP2E1 1271/4885
US-12018037-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound ORC3, LEF1, OCIAD1 CYP1A1 188/4885CYP1A2 779/4885CYP2E1 283/4885
US-10995088-B2 Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer LOXL1, LOXL3, LOXL2 CYP1A1 1061/4885CYP1A2 1416/4885CYP2E1 1271/4885
US-11608330-B2 Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer LOXL1, LOXL3, LOXL2 CYP1A1 1061/4885CYP1A2 1416/4885CYP2E1 1271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.